An Overview of Primary Immunodeficiency

Nazia Hossain

Primary immunodeficiency disorder (PID) result from defects in immune system development and/or function. It is more frequent than previously believed. The estimated prevalence of PID is 1 in 1200 with the exception of IgA deficiency (prevalence= 1 in 300-500)1.PIDs are distinct from secondary immunodeficiency which occurs due to other causes, such as viral or bacterial infections, malnutrition, or treatment with immunosuppressive drugs. The presentation of PIDs is highly variable. Most disorders involve increased susceptibility to infection. Several lists of warning signs of PID are established.

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