Bubble Continuous Positive Airway Pressure (Bubble CPAP) in PTLBW Neonates with Respiratory Distress

Liton Chandra Saha1, MAK Azad Chowdhury2, Md. Mahbubul Hoque3, Md. Abdulla Al
Mamun4, Maksudur Rahman5

Background: Bubble continuous positive airway pressure is a well-established
modality for providing ventilatory support to spontaneously breathing infants. It has
been used in a variety of clinical situations.
Objectives: To evaluate the immediate outcome of PTLBW neonates with respiratory
distress by using Bubble Continuous Positive Airway Pressure (BCPAP).
Materials and Methods: This Clinical Trial (Quasi-Experimental study) was
conducted from 1st April 2013 to 30th September 2014 in the SCABU of Dhaka Shishu
(Children) Hospital. Total 172 preterm babies with a gestational age <35 weeks,
presented with clinical signs of respiratory distress were included in the study and
among them 85 cases were taken as BCPAP group who were treated by bubble CPAP
and 87patients who could not be treated by BCPAP due to unavailability of BCPAP
machine at that time were taken as control. Effects of BCPAP were assessed by
comparing the clinical conditions, oxygen saturation and arterial blood gas status.
Written informed consent from guardian was taken.
Results: Mean gestational age, weight and age at the time of admission were
comparable in two groups (BCPAP vs Control: GA 31±1.61 vs 30±1.93 weeks, birth
weight 1454±284 vs 1435±228gm, age 28±13 vs 31±19hrs). It was found that duration
of O2 need was significantly (p<0.05) less in BCPAP group than the control group
(5.61±1.61 vs8.49±3.22 days), significantly (p<0.05) less duration to improve respiratory
distress (3.69±1.55 vs 7.67±2.76 days) and hospital stay (8.74±3.72 vs 12.67±11.75
days) was required in BCPAP group. Requirement of mechanical ventilation (IMV)
was also less in BCPAP group (27.06% vs 51.72%, P<0.05).
Conclusion: This study found that CPAP is an effective modality of treatment of
PTLBW neonates with respiratory distress.
Keywords: Bubble CPAP, PTLBW, Respiratory distress


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