Congenital Adrenal Hyperplasia (Salt Wasting)

Fahmida Zabeen1, M. Quamrul Hassan2, Nurun Naher3

The term congenital adrenal hyperplasia (CAH) involves a group of autosomal recessive disorders,
which involves a deficiency of an enzyme involved in the synthesis of cortisol, aldosterone, or both.1 Clinical
symptoms of the different forms of CAH result from deficiency or excess production of particular
hormones.2 More than 90% cases of Congenital Adrenal Hyperplasia (CAH) are caused by a defect in
the enzyme 21-hydroxylase.3CAH in most contexts refers to 21-hydroxylase deficiency.


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