X - Linked Agammaglobulinemia
Md. Yousuf Ahmed1, Md. Abdullah Al Mamun2, Abdul Jabbar3, Nadira Binta Haque4, Md. Mahbubul Hoque5
Agammaglobulinemia was the first primary immunodeficiency to be described in 1952 by Colonel Ogden Bruton who noted the absence of the “gammaglobulin”fraction on protein electrophoresis in a boy with recurrent bacterial sinopulmonary infections.1Subsequently, the gene responsible for X-Linked Agammaglobulinemia(XLA) was identified and named Bruton’styrosine kinase (BTK) at Xq21.3.